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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: ENSA All Species: 18.18
Human Site: S109 Identified Species: 40
UniProt: O43768 Number Species: 10
    Phosphosite Substitution
    Charge Score: 0
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O43768 NP_004427.1 121 13389 S109 D L P Q R K S S L V T S K L A
Chimpanzee Pan troglodytes XP_001169440 137 15291 S125 D L P Q R K S S L V T S K L A
Rhesus Macaque Macaca mulatta XP_001106271 164 18038 S152 D L P Q R K S S L V T S K L A
Dog Lupus familis XP_861020 132 14690 G109 P D K N L V T G D H I P T P Q
Cat Felis silvestris
Mouse Mus musculus P56212 112 12274 R101 T P Q D L P Q R K P S L V A S
Rat Rattus norvegicus P60841 121 13316 S109 D L P Q R K S S L V T S K L A
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001520850 143 15400 A112 N K Q L P A A A P D K A E V T
Chicken Gallus gallus Q5ZIF8 117 12707 Q105 P K P Q D L P Q R K S S L V A
Frog Xenopus laevis Q7ZXH9 125 13927 S109 D L P Q R K S S L V T S K L A
Zebra Danio Brachydanio rerio Q1L8X2 124 13737 P111 I P T P Q D L P Q R K N T I L
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster
Honey Bee Apis mellifera
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana P42759 260 29529 D148 E E N Q G V M D R I K E K F P
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 88.3 67 88.6 N.A. 71 98.3 N.A. 60.8 80.1 80 64.5 N.A. N.A. N.A. N.A. N.A.
Protein Similarity: 100 88.3 68.2 88.6 N.A. 78.5 99.1 N.A. 67.1 87.5 86.4 76.6 N.A. N.A. N.A. N.A. N.A.
P-Site Identity: 100 100 100 0 N.A. 0 100 N.A. 0 26.6 100 0 N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: 100 100 100 6.6 N.A. 13.3 100 N.A. 40 40 100 20 N.A. N.A. N.A. N.A. N.A.
Percent
Protein Identity: N.A. N.A. N.A. 21.9 N.A. N.A.
Protein Similarity: N.A. N.A. N.A. 32.6 N.A. N.A.
P-Site Identity: N.A. N.A. N.A. 13.3 N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. 26.6 N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 0 0 0 10 10 10 0 0 0 10 0 10 55 % A
% Cys: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % C
% Asp: 46 10 0 10 10 10 0 10 10 10 0 0 0 0 0 % D
% Glu: 10 10 0 0 0 0 0 0 0 0 0 10 10 0 0 % E
% Phe: 0 0 0 0 0 0 0 0 0 0 0 0 0 10 0 % F
% Gly: 0 0 0 0 10 0 0 10 0 0 0 0 0 0 0 % G
% His: 0 0 0 0 0 0 0 0 0 10 0 0 0 0 0 % H
% Ile: 10 0 0 0 0 0 0 0 0 10 10 0 0 10 0 % I
% Lys: 0 19 10 0 0 46 0 0 10 10 28 0 55 0 0 % K
% Leu: 0 46 0 10 19 10 10 0 46 0 0 10 10 46 10 % L
% Met: 0 0 0 0 0 0 10 0 0 0 0 0 0 0 0 % M
% Asn: 10 0 10 10 0 0 0 0 0 0 0 10 0 0 0 % N
% Pro: 19 19 55 10 10 10 10 10 10 10 0 10 0 10 10 % P
% Gln: 0 0 19 64 10 0 10 10 10 0 0 0 0 0 10 % Q
% Arg: 0 0 0 0 46 0 0 10 19 10 0 0 0 0 0 % R
% Ser: 0 0 0 0 0 0 46 46 0 0 19 55 0 0 10 % S
% Thr: 10 0 10 0 0 0 10 0 0 0 46 0 19 0 10 % T
% Val: 0 0 0 0 0 19 0 0 0 46 0 0 10 19 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _